Stanley Neufeld began his career in entertainment working odd jobs on the sets of Producers Releasing Corporation productions, founded by his father, producer Sigmund Neufeld, and uncle, director Sam Newfield. After serving in World War II in the Merchant Marines, Neufeld returned to Hollywood and worked as a second assistant director for PRC and Columbia Pictures on such films as Murder in My Business (1946), The Lady from Shanghai (1947), Money Madness (1948), State Department: File 649 (1949), Motor Patrol (1950) and Lost Continent (1951). In the early 1950s he was hired by legendary Western star Gene Autry as the assistant director and production manager for his Flying A Pictures series The Range Rider, Death Valley Days, Hawkeye and the Last of the Mohicans, Buffalo Bill, Jr., Annie Oakley and The Gene Autry Show.
In 1960 Neufeld was hired as the production executive for the series Naked City’s New York shooting unit. He remained on the east coast for nearly 20 years as a production executive on the series The Patty Duke Show and The Trials of O’Brien, along with the feature films Popi (1969), Loving (1970), Cotton Comes to Harlem (1970), Come Back, Charleston Blue (1972), Death Wish (1974), Mandingo (1975), Lipstick (1976), and Orca (1977). In the late 1970s he moved back to Los Angeles as a production executive for Orion Pictures, overseeing the series Cagney & Lacey. During his time at Orion he oversaw the production of such films as Amadeus (1984), Platoon (1986), Dances with Wolves (1990), and The Silence of the Lambs (1991).